SCHEMBL2835666

SCHEMBL2835666

COC(C)N1C(=O)C=CC1=O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.38
GSK3A P49840 2/20 0.38
GSK3B P49841 2/20 0.38
GMNN O75496 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21728710 0.85 GSK3A (0.31) MGLLGSK3AGSK3B
SCHEMBL11939115 0.78 MGLL (0.36) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL4309020 0.77 MGLL (0.39) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL2607935 0.75 MGLL (0.39) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL9080470 0.75 MGLL (0.33) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL3790252 0.75 MGLL (0.33) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL1970949 0.74 ALDH1A1 (0.32) MGLLGSK3AGSK3BGMNNALDH1A1
SCHEMBL3173583 0.73 TSHR (0.41) MGLLGSK3AGSK3BALDH1A1MAPT
SCHEMBL9668855 0.73 MGLL (0.32) MGLLGSK3AGSK3B
SCHEMBL43978 0.73 MGLL (0.45) MGLLGSK3AGSK3BGMNNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114008061-B Radiolabelled MOEM oligonucleotides and methods of making same 豪夫迈·罗氏有限公司 2024-03-12 CN disclosed
US-20170157264-A1 CROSS-LINKERS AND THEIR USES IMMUNOGEN, INC. 2017-06-08 US disclosed
US-9268076-B2 Optical compensation layer, optical compensation film, and processes for producing these TOSOH CORPORATION (JP) 2016-02-23 US disclosed
EP-2138871-B1 OPTICAL COMPENSATION LAYER, OPTICALLY COMPENSATING FILM, AND PROCESSES FOR PRODUCING THESE TOSOH CORP (JP) 2015-06-17 EP disclosed
CN-101669049-B Optical compensation films, optically compensating film, and processes for producing these TOSOH CORP 2013-10-30 CN disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20100240855-A1 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2010-09-23 US disclosed
US-20100110353-A1 OPTICAL COMPENSATION LAYER, OPTICAL COMPENSATION FILM, AND PROCESSES FOR PRODUCING THESE TOSOH CORPORATION (JP) 2010-05-06 US disclosed
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
CN-101669049-A Optical compensation films, optically compensating film, and processes for producing these TOSOH CORP 2010-03-10 CN disclosed
EP-2138871-A1 OPTICAL COMPENSATION FILMS, OPTICALLY COMPENSATING FILM, AND PROCESSES FOR PRODUCING THESE Tosoh Corporation (JP) 2009-12-30 EP disclosed
US-7579444-B2 Polymer-factor IX moiety conjugates NEKTAR THERAPEUTICS AL, CORPORATION (US) 2009-08-25 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 MGLL 4700/4885GSK3A 2699/4885GSK3B 2311/4885
US-20170157264-A1 CROSS-LINKERS AND THEIR USES MTCL3, DCLRE1A, PCNA MGLL 4214/4885GSK3A 4548/4885GSK3B 4523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.