Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 14/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 14/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19709492 | 0.87 | LIPC (0.42) | LIPCLIPGEGLN1FLT1EGLN3 | |
| SCHEMBL20972694 | 0.74 | HPGD (0.44) | LIPCLIPG | |
| SCHEMBL19709505 | 0.72 | LIPC (0.56) | LIPCLIPGEGLN1 | |
| SCHEMBL20972622 | 0.71 | LIPG (0.48) | LIPCLIPG | |
| SCHEMBL19709635 | 0.71 | LIPG (0.48) | LIPCLIPG | |
| SCHEMBL20972624 | 0.68 | LIPG (0.64) | LIPCLIPG | |
| SCHEMBL19709639 | 0.62 | LIPG (0.65) | LIPCLIPG | |
| SCHEMBL20972671 | 0.60 | LIPC (0.49) | LIPCLIPG | |
| SCHEMBL21061889 | 0.54 | NPC1 (0.41) | — | |
| SCHEMBL5514028 | 0.51 | POLB (0.49) | EGLN1FLT1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214005-A1 | 2-(BENZOTHIAZOL-2-YL)-2-CYANO-ACETAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-14 | — | — | WO | disclosed |