Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 20/20 | 0.48 |
| ▸ | LIPC | P11150 | 14/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20972622 | 0.87 | LIPG (0.48) | LIPGLIPC | |
| SCHEMBL19709505 | 0.78 | LIPC (0.56) | LIPGLIPC | |
| SCHEMBL20972710 | 0.74 | LIPG (0.44) | LIPGLIPC | |
| SCHEMBL20972752 | 0.73 | LIPG (0.65) | LIPGLIPC | |
| SCHEMBL19709639 | 0.73 | LIPG (0.65) | LIPGLIPC | |
| SCHEMBL20972617 | 0.72 | LIPG (0.75) | LIPGLIPC | |
| SCHEMBL19709499 | 0.71 | LIPC (0.42) | LIPGLIPC | |
| SCHEMBL19709492 | 0.71 | LIPC (0.42) | LIPGLIPC | |
| SCHEMBL20999021 | 0.68 | LIPG (0.70) | LIPGLIPC | |
| SCHEMBL20972736 | 0.68 | LIPC (0.80) | LIPGLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214005-A1 | 2-(BENZOTHIAZOL-2-YL)-2-CYANO-ACETAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-14 | — | — | WO | disclosed |