Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18349843 | 0.85 | HDAC1 (0.45) | HDAC6SMN1; SMN2HDAC3HDAC1GAA | |
| SCHEMBL20371134 | 0.85 | GAA (0.45) | HDAC6HDAC3HDAC1GAAALDH1A1 | |
| SCHEMBL5964225 | 0.83 | GAA (0.43) | HDAC6HDAC3HDAC1GAAALDH1A1 | |
| SCHEMBL3839548 | 0.83 | GAA (0.43) | HDAC6HDAC3HDAC1GAAALDH1A1 | |
| SCHEMBL20371135 | 0.82 | HDAC6 (0.43) | HDAC6GAAALDH1A1KMT2A | |
| SCHEMBL4447235 | 0.80 | KMT2A (0.52) | HDAC6SMN1; SMN2KMT2A | |
| SCHEMBL27240989 | 0.76 | SLC6A9 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL27240993 | 0.76 | SLC6A9 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL19463708 | 0.75 | HDAC6 (0.43) | HDAC6SMN1; SMN2HDAC3HDAC1ALDH1A1 | |
| SCHEMBL19463709 | 0.75 | HDAC6 (0.43) | HDAC6SMN1; SMN2HDAC3HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | CD2BP2, CACYBP, CALCOCO2 | HDAC6 1806/4885SMN1; SMN2 2328/4885HDAC3 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.