Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 11/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684585 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL19667229 | 0.77 | PNMT (0.44) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL25281145 | 0.74 | PNMT (0.46) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL30183105 | 0.74 | PNMT (0.46) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL19678853 | 0.73 | CHRNB2 (0.38) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL30207837 | 0.73 | PNMT (0.48) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL19667407 | 0.73 | PNMT (0.48) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL25281366 | 0.73 | PNMT (0.45) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL31186539 | 0.73 | PNMT (0.45) | CHRNB2CHRNA4PNMTADRA2AADRA2B | |
| SCHEMBL19711565 | 0.71 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464249-B1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2017213825-A1 | TREATMENT METHODS HAVING REDUCED DRUG-RELATED TOXICITY AND METHODS OF IDENTIFYING THE LIKELIHOOD OF PATIENT HARM FROM PRESCRIBED MEDICATIONS | TABULA RASA HEALTHCARE, INC. (US) | 2017-12-14 | — | — | WO | disclosed |