SCHEMBL19711964

SCHEMBL19711964

O=C(O)c1ccc(C(F)(F)C(F)(F)F)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HA1 P13674 3/20 0.52
P4HTM Q9NXG6 2/20 0.52
MIF P14174 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48
GABRQ Q9UN88 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL186213 0.85 L3MBTL1 (0.57) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL29418677 0.85 L3MBTL1 (0.57) P4HA1P4HTMMIFL3MBTL1GABRP
Hydrochloric Acid SCHEMBL21767713 0.83 L3MBTL1 (0.56) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL1420731 0.81 NAPRT (0.53) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL15718539 0.81 P4HA1 (0.52) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL30521254 0.81 P4HA1 (0.52) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL25804618 0.81 P4HA1 (0.52) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL29534992 0.81 P4HA1 (0.47) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL28970323 0.79 P4HA1 (0.57) P4HA1P4HTMMIFL3MBTL1GABRP
SCHEMBL1070876 0.77 P4HA1 (0.55) P4HA1P4HTMMIFL3MBTL1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257853-B1 CONDENSED HETEROCYCLIC COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT NISSAN CHEMICAL CORP (JP) 2021-11-10 EP disclosed
US-20210017194-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES NISSAN CHEMICAL CORPORATION (JP) 2021-01-21 US disclosed
US-10882869-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-10464950-B2 Condensed heterocyclic compounds and pesticides NISSAN CHEMICAL CORPORATION (JP) 2019-11-05 US disclosed
US-20180022760-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-01-25 US disclosed
EP-3257853-A1 CONDENSED HETEROCYCLIC COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2017-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022760-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES HDAC3, CHRM3, NR1D2 P4HA1 1299/4885P4HTM 1985/4885MIF 4779/4885
US-10882869-B2 Condensed heterocyclic compounds and pesticides CNPY3, CNPY2, CHRM1 P4HA1 1575/4885P4HTM 3219/4885MIF 4665/4885
US-20210017194-A1 CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES HDAC3, CHRM3, NR1D2 P4HA1 1299/4885P4HTM 1985/4885MIF 4779/4885
US-10464950-B2 Condensed heterocyclic compounds and pesticides HDAC3, CHRM3, NR1D2 P4HA1 1299/4885P4HTM 1985/4885MIF 4779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.