Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712469 | 0.90 | ALOX5AP (0.37) | PIK3CATRPC6MTOR | |
| SCHEMBL19712457 | 0.90 | ALOX5AP (0.34) | PIK3CAMTOR | |
| SCHEMBL19712467 | 0.86 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL12502021 | 0.86 | KDM4E (0.38) | KDM4ENPC1ALDH1A1GLAPOLB | |
| SCHEMBL19712500 | 0.85 | PIK3CA (0.31) | PIK3CA | |
| SCHEMBL19712473 | 0.84 | MAT2A (0.34) | PIK3CAMTOR | |
| SCHEMBL12502311 | 0.84 | PIK3CA (0.36) | KDM4ENPC1ALDH1A1GLAPOLB | |
| SCHEMBL19712460 | 0.83 | — | — | |
| Potassium Ion SCHEMBL12501963 | 0.83 | PIK3CA (0.34) | KDM4ENPC1ALDH1A1GLAPOLB | |
| SCHEMBL19712468 | 0.82 | MAOA (0.34) | KDM4EALDH1A1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670410-B1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | EMERGENT PRODUCT DEV GAITHERSBURG INC (US) | 2017-12-20 | — | — | EP | claimed |