Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | KLK1 | P06870 | 2/20 | 0.45 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066894 | 0.80 | ERN1 (0.59) | — | |
| SCHEMBL1360246 | 0.80 | ERN1 (0.59) | — | |
| SCHEMBL18425254 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTCYP1A2SLC2A1 | |
| SCHEMBL10388887 | 0.78 | MTNR1A (0.51) | ALDH1A1CYP3A4MTNR1AMTNR1BMAPT | |
| SCHEMBL30066982 | 0.78 | MTNR1A (0.51) | ALDH1A1CYP3A4MTNR1AMTNR1BMAPT | |
| SCHEMBL15961373 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP3A4MAPK1KDM4E | |
| SCHEMBL11772378 | 0.77 | POLB (0.48) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL28948948 | 0.77 | CYP1A2 (0.43) | ALDH1A1MAPK1KDM4EMAPTCYP1A2 | |
| SCHEMBL8153548 | 0.77 | ERN1 (0.45) | ALDH1A1MAPK1KDM4EMAPTCYP1A2 | |
| SCHEMBL9747620 | 0.75 | MTNR1A (0.55) | ALDH1A1HPGDCYP3A4MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354727-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2020-10-07 | — | — | EP | claimed |
| EP-2385983-B1 | TRANSAMINASE POLYPEPTIDES | CODEXIS INC (US) | 2017-12-20 | — | — | EP | claimed |