SCHEMBL19712901

SCHEMBL19712901

[CH2]CNC(=O)Oc1ccc2cc(I)ccc2c1-c1c(OC(=O)NC[CH2])ccc2cc(C#N)ccc12

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 2/20 0.44
TBXA2R P21731 3/20 0.36
MGLL Q99685 2/20 0.36
MAP2K1 Q02750 8/20 0.34
F2 P00734 1/20 0.33
PLG P00747 1/20 0.33
PLAU P00749 1/20 0.33
KLKB1 P03952 1/20 0.33
PRSS1 P07477 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712913 0.93 NCEH1 (0.49) NCEH1MGLLF2PLGPLAU
SCHEMBL19712952 0.90 NCEH1 (0.35) NCEH1MGLL
SCHEMBL19712896 0.88 NCEH1 (0.45) NCEH1MGLLF2PLGPLAU
SCHEMBL17825877 0.87 NCEH1 (0.49) NCEH1TBXA2RMGLL
SCHEMBL19712898 0.87 NCEH1 (0.44) NCEH1TBXA2RMGLLF2PLG
SCHEMBL19712923 0.83 NCEH1 (0.40) NCEH1TBXA2RMGLLMAP2K1
SCHEMBL20484105 0.81 NCEH1 (0.42) NCEH1TBXA2RMGLLMAP2K1F2
SCHEMBL19712947 0.75 NCEH1 (0.48) NCEH1
SCHEMBL19712933 0.75 FAAH (0.40) NCEH1
SCHEMBL20483985 0.73 NCEH1 (0.44) NCEH1TBXA2RMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11267943-B2 Film structure containing a photopolymer layer for holographic exposure and a coating layer of high resistance COVESTRO DEUTSCHLAND AG (DE) 2022-03-08 US disclosed
US-20210292505-A1 FILM STRUCTURE CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A COATING LAYER OF HIGH RESISTANCE COVESTRO DEUTSCHLAND AG (DE) 2021-09-23 US disclosed
US-20200166888-A1 HOLOGRAPHIC MEDIUM CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A HIGHLY RESISTANT COATING LAYER COVESTRO DEUTSCHLAND AG (DE) 2020-05-28 US disclosed
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers COVESTRO DEUTSCHLAND AG (DE) 2019-03-26 US disclosed
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS NEFM, ACR, DIAPH1 NCEH1 4259/4885TBXA2R 3075/4885MGLL 2733/4885
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers NEFM, ACR, DIAPH1 NCEH1 4259/4885TBXA2R 3075/4885MGLL 2733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.