Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17901119 | 1.00 | CA1 (0.47) | CA1CA2IDO1AGXTSLC6A4 | |
| SCHEMBL19725384 | 0.82 | IDO1 (0.50) | CA1CA2IDO1AGXTSLC6A4 | |
| SCHEMBL7068905 | 0.82 | IDO1 (0.44) | CA1CA2IDO1AGXTSLC6A4 | |
| SCHEMBL20370148 | 0.80 | RCE1 (0.51) | CA1CA2HTT | |
| SCHEMBL13773424 | 0.80 | RCE1 (0.51) | CA1CA2HTT | |
| SCHEMBL29127966 | 0.79 | IDO1 (0.47) | CA1CA2IDO1AGXTSLC6A4 | |
| SCHEMBL14567491 | 0.78 | ALDH1A1 (0.49) | CA1CA2IDO1AGXTSLC6A4 | |
| SCHEMBL17760946 | 0.78 | RCE1 (0.50) | CA1CA2IDO1AGXTSLC6A4 | |
| SCHEMBL21440869 | 0.78 | ATM (0.48) | CA1CA2POLBSMN1; SMN2AOC3 | |
| SCHEMBL28508515 | 0.78 | ATM (0.48) | CA1CA2POLBSMN1; SMN2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205398-B | Pyridine amide compounds having fungicidal activity | 美国陶氏益农公司 | 2020-08-21 | — | — | CN | disclosed |
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-29 | — | — | US | disclosed |
| US-20180000084-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC | 2018-01-04 | — | — | US | disclosed |
| US-20170360038-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360038-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | CA1 2106/4885CA2 247/4885IDO1 1393/4885 |
| US-10188109-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | CA1 2106/4885CA2 247/4885IDO1 1393/4885 |
| US-20180000084-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CYP1A2, CYP51A1 | CA1 1685/4885CA2 344/4885IDO1 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.