Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.91 |
| ▸ | HPGD | P15428 | 3/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meradimate SCHEMBL6851307 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL29461397 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL14697604 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL18884 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL339007 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL18989595 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL14637358 | 0.95 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL29209240 | 0.94 | ALDH1A1 (0.98) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL8329573 | 0.94 | ALDH1A1 (0.98) | ALDH1A1HPGDKDM4EMAPTMAPK1 | |
| Meradimate SCHEMBL27915999 | 0.92 | ALDH1A1 (0.93) | ALDH1A1HPGDKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651732-A1 | LIGHT AESTHETIC SUNSCREEN COMPOSITIONS | Johnson & Johnson Consumer Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3471694-A1 | SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS | Johnson & Johnson Consumer Inc. (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2019014568-A1 | LIGHT AESTHETIC SUNSCREEN COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| WO-2017218390-A1 | SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS | JOHNSON & JOHNSON CONSUMER INC. (US) | 2017-12-21 | — | — | WO | disclosed |