Meradimate

Meradimate

SCHEMBL339007

CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)c1ccccc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 1.00
HPGD P15428 3/20 1.00
KDM4E B2RXH2 3/20 0.58
MAPT P10636 2/20 0.58
MAPK1 P28482 2/20 0.58
GAA P10253 1/20 0.58
ACLY P53396 1/20 0.53
LMNA P02545 2/20 0.51
NPSR1 Q6W5P4 3/20 0.50
CYP19A1 P11511 2/20 0.50
TSHR P16473 2/20 0.49
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
P2RX4 Q99571 1/20 0.47
EPHX1 P07099 2/20 0.46
POLB P06746 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
MITF O75030 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Meradimate SCHEMBL29461397 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL14697604 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL14637358 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL18884 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL18989595 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL6851307 1.00 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL29209240 0.99 ALDH1A1 (0.98) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL8329573 0.99 ALDH1A1 (0.98) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL27915999 0.96 ALDH1A1 (0.93) ALDH1A1HPGDKDM4EMAPTMAPK1
Meradimate SCHEMBL19717873 0.95 ALDH1A1 (0.91) ALDH1A1HPGDKDM4EMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1693 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735958-A1 PHOTORESIST PATTERNING IN MULTI-DEPTH NANOWELLS Illumina, Inc. (US) 2026-05-06 EP claimed
US-20260060907-A1 GADUSOL-CONTAINING SUNSCREEN FORMULATIONS ARCAEA LLC (US) 2026-03-05 US claimed
US-20250332079-A1 TOPICAL SUNSCREEN CONCEPT MATRIX SOLUTIONS 2025-10-30 US claimed
EP-4630153-A1 ETCH-FREE PHOTORESIST PATTERNING IN MULTI-DEPTH NANOWELLS Illumina, Inc. (US) 2025-10-15 EP claimed
US-12427151-B2 Compositions and method of treating cancer THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-30 US claimed
EP-4004021-B1 POLYPEPTIDES HAVING ANTI-SENESCENT EFFECTS AND USES THEREOF ONESKIN INC (US) 2025-09-03 EP claimed
EP-2384193-B1 VITAMIN D PROMOTING SUNSCREEN ARMSTRONG ERNEST T (US) 2025-08-06 EP claimed
US-20250228757-A1 SUNSCREEN COMPOUNDS AND FORMULATIONS OREGON STATE UNIVERSITY (US) 2025-07-17 US claimed
EP-4580590-A1 GADUSOL-CONTAINING SUNSCREEN FORMULATIONS Arcaea, LLC (US) 2025-07-09 EP claimed
US-12337058-B1 Sunscreen formulations and methods of making and using the same W.S. Badger Company (US) 2025-06-24 US claimed
EP-1768644-A1 LIGHT PROTECTING-EFFECTIVE COSMETIC OR DERMATOLOGICAL PREPARATIONS Ciba SC Holding AG (CH) 2007-04-04 EP claimed
CN-1849083-A Substrates and devices for applying a lip care formulation KIMBERLY CLARK CO (US) 2006-10-18 CN claimed
US-20060210496-A1 COMPOSITIONS FOR SKIN PROTECTION FROM ULTRAVIOLET DAMAGE SAKURA PROPERTIES, LLC 2006-09-21 US claimed
EP-1675490-A1 SUBSTRATES AND DEVICES FOR APPLYING A LIP CARE FORMULATION Kimberly-Clark Worldwide, Inc. (US) 2006-07-05 EP claimed
WO-2006008252-A1 LIGHT PROTECTING-EFFECTIVE COSMETIC OR DERMATOLOGICAL PREPARATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-01-26 WO claimed
WO-2005041711-A1 SUBSTRATES AND DEVICES FOR APPLYING A LIP CARE FORMULATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-05-12 WO claimed
US-20050066463-A1 Substrates and devices for applying a lip care formulation KIMBERLY-CLARK WORLDWIDE, INC. 2005-03-31 US claimed
US-6090370-A TREATING THE HAIR WITH A COSMETIC FORMULATION COMPRISING PROTECTIVE AMONUNT OF A BENZOTRIAZOLE COMPOUND FOR PROTECTING HUMAN HAIR FROM HARMFUL EFFECT OF ULTRAVIOLET RADIATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-07-18 US claimed
US-5567420-A SUCH AS SUNSCREEN AGENT GE CANADA FINANCE HOLDING COMPANY (CA) 1996-10-22 US claimed
WO-1996014826-A1 LOTION WHICH IS TEMPORARILY COLORED UPON APPLICATION SEEUV (US) 1996-05-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228757-A1 SUNSCREEN COMPOUNDS AND FORMULATIONS ACSS2, FADS1, FADS2 ALDH1A1 189/4885HPGD 1624/4885KDM4E 2337/4885
US-20250332079-A1 TOPICAL SUNSCREEN SUN2, CYP51A1, DSG1 ALDH1A1 1641/4885HPGD 139/4885KDM4E 837/4885
US-20260060907-A1 GADUSOL-CONTAINING SUNSCREEN FORMULATIONS XPA, ERCC1, ERCC2 ALDH1A1 1935/4885HPGD 710/4885KDM4E 4801/4885
US-12427151-B2 Compositions and method of treating cancer ERCC5, ERCC1, XPA ALDH1A1 2039/4885HPGD 925/4885KDM4E 3262/4885
US-20060210496-A1 COMPOSITIONS FOR SKIN PROTECTION FROM ULTRAVIOLET DAMAGE FUCA1, XRCC6, XRCC5 ALDH1A1 1322/4885HPGD 1400/4885KDM4E 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.