Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.32 |
| ▸ | GLP1R | P43220 | 5/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425936 | 0.82 | TSHR (0.51) | TSHRTHRBLPAR1LPAR2HPGD | |
| SCHEMBL8906649 | 0.82 | THRB (0.41) | TSHRTHRBDNM1HTTALDH1A1 | |
| SCHEMBL29217398 | 0.81 | THRB (0.43) | TSHRTHRBHDAC3HDAC4HDAC1 | |
| SCHEMBL4915028 | 0.81 | TSHR (0.54) | TSHRTHRBLPAR1LPAR2HPGD | |
| SCHEMBL24099523 | 0.81 | TSHR (0.50) | TSHRTHRBLPAR1LPAR2HPGD | |
| SCHEMBL4916547 | 0.80 | TSHR (0.57) | TSHRTHRBLPAR1LPAR2HPGD | |
| SCHEMBL28538863 | 0.80 | TSHR (0.48) | TSHRTHRBDNM1HTTALDH1A1 | |
| SCHEMBL27756449 | 0.80 | TSHR (0.48) | TSHRTHRBDNM1HTTALDH1A1 | |
| SCHEMBL29191364 | 0.80 | TSHR (0.48) | TSHRTHRBDNM1HTTALDH1A1 | |
| SCHEMBL4918092 | 0.79 | TSHR (0.51) | TSHRTHRBHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468633-A1 | SURFACE-COATED CONTINUOUS GLUCOSE MONITORS | Massachusetts Institute Of Technology (US) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017218520-A1 | SURFACE-COATED CONTINUOUS GLUCOSE MONITORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-21 | — | — | WO | disclosed |