Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191364 | 0.95 | TSHR (0.48) | THRBTSHRDGKATDP1POLB | |
| SCHEMBL27756449 | 0.95 | TSHR (0.48) | THRBTSHRDGKATDP1POLB | |
| SCHEMBL28538863 | 0.95 | TSHR (0.48) | THRBTSHRDGKATDP1POLB | |
| SCHEMBL16374096 | 0.82 | DGKA (0.43) | TSHRDGKATDP1DNM1ALDH1A1 | |
| SCHEMBL19717992 | 0.82 | TSHR (0.36) | THRBTSHRHTTDNM1ALDH1A1 | |
| SCHEMBL1696757 | 0.82 | THRB (0.57) | THRBTSHRDGKATDP1POLB | |
| SCHEMBL16312502 | 0.81 | DGKA (0.43) | TSHRDGKATDP1DNM1ALDH1A1 | |
| SCHEMBL16480294 | 0.80 | DGKA (0.45) | THRBTSHRDGKATDP1DNM1 | |
| SCHEMBL275245 | 0.80 | DGKA (0.59) | THRBTSHRDGKATDP1POLB | |
| SCHEMBL8095315 | 0.80 | DGKA (0.51) | TSHRDGKATDP1DNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7258248-A | — | — | None | — | — | JP | disclosed |
| US-5670657-A | DISULFIDE CYCLIC COMPOUND FOR PRECIOUS METAL ADHESIVES | KABUSHIKI KAISHA SHOFU (JP) | 1997-09-23 | — | — | US | disclosed |
| JP-H07258248-A | (METH)ACRYLATE ESTER DERIVATIVE | SHIYOUFUU:KK | 1995-10-09 | — | — | JP | disclosed |