Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910192 | 0.94 | CA1 (0.46) | TSHRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL6686810 | 0.91 | TSHR (0.50) | TSHRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3475755 | 0.88 | TSHR (0.44) | TSHRKDM4EALDH1A1CA1CA2 | |
| SCHEMBL17183610 | 0.86 | TP53 (0.43) | TSHRKDM4EALDH1A1CA1CA2 | |
| SCHEMBL21768343 | 0.86 | TP53 (0.43) | TSHRKDM4EALDH1A1CA1CA2 | |
| SCHEMBL1977054 | 0.84 | ALDH1A1 (0.53) | TSHRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL25394857 | 0.83 | NPC1 (0.47) | TSHRKDM4EALDH1A1GAAEGFR | |
| SCHEMBL483513 | 0.83 | NPC1 (0.47) | TSHRKDM4EALDH1A1GAAEGFR | |
| SCHEMBL25395879 | 0.83 | NPC1 (0.47) | TSHRKDM4EALDH1A1GAAEGFR | |
| SCHEMBL22463700 | 0.82 | CA2 (0.52) | TSHRMAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | US | disclosed |
| US-11590233-B2 | Porphyrin compounds and compositions useful for treating cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-02-28 | — | — | US | disclosed |
| US-20190184021-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | ONCOSELECT THERAPEUTICS, LLC | 2019-06-20 | — | — | US | disclosed |
| EP-3471774-A1 | PORPHYRIN COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING CANCER | Oncoselect Therapeutics, LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017218959-A1 | PORPHYRIN COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING CANCER | ONCOSELECT THERAPEUTICS, LLC (US) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | KIT, HCCS, PPIF | TSHR 4567/4885KDM4E 2828/4885ALDH1A1 2847/4885 |
| US-11590233-B2 | Porphyrin compounds and compositions useful for treating cancer | KIT, HCCS, PPIF | TSHR 4567/4885KDM4E 2828/4885ALDH1A1 2847/4885 |
| US-20190184021-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | TK2, KIT, HCCS | TSHR 4629/4885KDM4E 2307/4885ALDH1A1 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.