Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852253 | 0.89 | TLR2 (0.51) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL31493934 | 0.89 | TLR2 (0.51) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL5312217 | 0.89 | TLR2 (0.51) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL29521704 | 0.89 | TLR2 (0.51) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL29400519 | 0.89 | TLR2 (0.51) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL30546904 | 0.87 | TLR2 (0.48) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL12852250 | 0.86 | TLR2 (0.49) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL29531876 | 0.86 | TLR2 (0.54) | TLR2TLR1MDM2KLK7KLK5 | |
| SCHEMBL16925663 | 0.82 | KMT2A (0.53) | TLR2TLR1MDM2KMT2A | |
| SCHEMBL20435349 | 0.79 | KMT2A (0.52) | TLR2TLR1MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845493-B2 | Tunable fluorescence using cleavable linkers | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-12-19 | — | — | US | disclosed |