Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 14/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718516 | 0.80 | PARG (0.37) | PARGPDK2 | |
| SCHEMBL31120210 | 0.77 | LMNA (0.44) | — | |
| SCHEMBL13278527 | 0.74 | ALDH1A1 (0.50) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL5014621 | 0.73 | HTR2A (0.43) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL5062909 | 0.73 | HTR2A (0.43) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL283246 | 0.73 | HTR2A (0.48) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL29363404 | 0.73 | HTR2A (0.48) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL1649136 | 0.72 | PDK2 (0.47) | PDK2 | |
| SCHEMBL21759261 | 0.72 | HTR2A (0.46) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL24618321 | 0.71 | NPC1 (0.36) | PDK2MLNRNR1I2CHRM2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845334-B1 | High-efficiency organic glass scintillators | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2017-12-19 | — | — | US | disclosed |