Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 9/20 | 0.66 |
| ▸ | FKBP1A | P62942 | 17/20 | 0.63 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | FKBP2 | P26885 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16595025 | 1.00 | FKBP5 (0.66) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL18120812 | 0.95 | FKBP5 (0.60) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16586025 | 0.94 | FKBP5 (0.68) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL19719599 | 0.94 | FKBP5 (0.68) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16586028 | 0.94 | FKBP5 (0.68) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16595027 | 0.93 | FKBP5 (0.66) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL19719684 | 0.93 | FKBP5 (0.66) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16586167 | 0.93 | FKBP5 (0.66) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL18122835 | 0.90 | FKBP5 (0.71) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL21540227 | 0.90 | FKBP5 (0.71) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246413-B2 | Selective FKBP51 ligands for treatment of psychiatric disorders | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180072667-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | HAUSCH, FELIX (DE) | 2018-03-15 | — | — | US | disclosed |
| US-9845292-B2 | Selective FKBP51 ligands for treatment of psychiatric disorders | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072667-A1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | FKBP5, FKBP1A, FKBP3 | FKBP5 1/4885FKBP1A 2/4885FKBP1B 4/4885 |
| US-10246413-B2 | Selective FKBP51 ligands for treatment of psychiatric disorders | FKBP5, FKBP1A, FKBP3 | FKBP5 1/4885FKBP1A 2/4885FKBP1B 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.