SCHEMBL19720248

SCHEMBL19720248

CC(CC(C)(C)OCc1ccccc1)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
SLC6A2 P23975 2/20 0.36
TAAR1 Q96RJ0 2/20 0.36
MAOA P21397 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
CYP2A6 P11509 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
IDO1 P14902 1/20 0.34
TRPA1 O75762 1/20 0.34
BCHE P06276 1/20 0.34
ALDH1A1 P00352 2/20 0.33
AGXT P21549 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21467443 0.87 SLC6A2 (0.38) TSHRSLC6A2TAAR1MAOASLC6A4
SCHEMBL21467431 0.83 TSHR (0.36) TSHRSLC6A2TAAR1MAOASLC6A4
SCHEMBL21467432 0.83 SLC6A2 (0.35) TSHRSLC6A2TAAR1MAOASLC6A4
SCHEMBL15930165 0.82 TSHR (0.41) TSHRSLC6A2TAAR1MAOASLC6A4
SCHEMBL19720286 0.79 TRPA1 (0.43) TSHRSLC6A2TAAR1MAOASLC6A4
SCHEMBL14667579 0.76 SIGMAR1 (0.50) SLC6A2TAAR1MAOASLC6A4SLC6A3
SCHEMBL21850320 0.76 TSHR (0.42) TSHRALDH1A1LMNAHPGDMAPK1
SCHEMBL19719631 0.76 CA1 (0.49) TSHRHTT
SCHEMBL18120841 0.76 CA1 (0.49) TSHRHTT
SCHEMBL11938479 0.75 TSHR (0.35) TSHRSLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3077056-B1 STYLING COMPOSITION FOR HAIR HENKEL AG & CO KGAA (DE) 2017-12-20 EP disclosed