Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21850454 | 0.88 | ALDH1A1 (0.38) | ALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL21850459 | 0.86 | ALOX15 (0.33) | — | |
| SCHEMBL21850356 | 0.86 | KMT2A (0.37) | TSHRALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL21850322 | 0.77 | NAAA (0.32) | LMNA | |
| SCHEMBL4965733 | 0.77 | TSHR (0.53) | TSHR | |
| SCHEMBL11938480 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1MAPK1L3MBTL1CTSS | |
| SCHEMBL19720248 | 0.76 | TSHR (0.36) | TSHRALDH1A1MAPK1LMNAHPGD | |
| SCHEMBL21467431 | 0.76 | TSHR (0.36) | TSHRALDH1A1MAPK1LMNAHPGD | |
| SCHEMBL19720286 | 0.76 | TRPA1 (0.43) | TSHRALDH1A1MAPK1LMNAHPGD | |
| SCHEMBL15930165 | 0.75 | TSHR (0.41) | TSHRALDH1A1MAPK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240408-B1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-04-08 | — | — | EP | disclosed |