Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30854371 | 0.82 | CYP1A2 (0.58) | CYP1A2MAPK1SMN1; SMN2SLC6A1GLA | |
| SCHEMBL30854439 | 0.80 | CYP1A2 (0.60) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL18939342 | 0.77 | CYP1A2 (0.51) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL8947664 | 0.75 | — | — | |
| SCHEMBL8377176 | 0.75 | CYP1A2 (0.78) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL3409970 | 0.74 | GLA (0.45) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL14671225 | 0.73 | HSD17B10 (0.41) | TSHR | |
| SCHEMBL857572 | 0.71 | SMN1; SMN2 (0.95) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| SCHEMBL472290 | 0.70 | SMN1; SMN2 (1.00) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 | |
| Hydrochloric Acid SCHEMBL946654 | 0.70 | SMN1; SMN2 (0.91) | CYP1A2MAPK1SMN1; SMN2LMNASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257848-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR ACTIVITY | Novartis AG (CH) | 2017-12-20 | — | — | EP | disclosed |