SCHEMBL857572

SCHEMBL857572

O=C(O)CCCN1CCCC1

nearest known ligand 0.95

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.95
CYP1A2 P05177 1/20 0.95
MAPK1 P28482 1/20 0.95
ALDH1A1 P00352 5/20 0.52
MAPT P10636 3/20 0.52
POLB P06746 1/20 0.52
HRH3 Q9Y5N1 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GLA P06280 1/20 0.47
ALOX15 P16050 1/20 0.46
LMNA P02545 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 1/20 0.44
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL946654 0.98 SMN1; SMN2 (0.91) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
Bromide SCHEMBL11793837 0.98 SMN1; SMN2 (0.91) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
SCHEMBL1858113 0.98 SMN1; SMN2 (1.00) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
SCHEMBL472290 0.98 SMN1; SMN2 (1.00) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL9870336 0.96 CYP1A2 (0.96) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL11544283 0.96 CYP1A2 (0.96) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL1127792 0.96 CYP1A2 (0.96) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
Methane SCHEMBL11633126 0.94 CYP1A2 (0.92) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
SCHEMBL1856267 0.93 CYP1A2 (0.83) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT
SCHEMBL9151071 0.91 CYP1A2 (0.80) SMN1; SMN2CYP1A2MAPK1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277012-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. 2025-09-04 US claimed
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PSOMAGEN, INC. (US) 2022-08-23 US claimed
US-20210128498-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE MACROGEN INC. (KR) 2021-05-06 US claimed
CN-111163761-A Targeted drugs related to trimethylamine and/or trimethylamine-N-oxide 普梭梅根公司 2020-05-15 CN claimed
US-20190050525-A1 RIESKE-TYPE OXYGENASE/REDUCTASE TARGETED DRUGS FOR DIAGNOSTIC AND TREATMENT OF DISEASES PSOMAGEN, INC. 2019-02-14 US claimed
US-20100113450-A1 Agent for Preventing and Alleviating Wrinkles SHISEIDO COMPANY LTD. (JP) 2010-05-06 US claimed
EP-2123253-A1 WRINKLING-PREVENTING AND -MODIFYING AGENT Shiseido Company, Ltd. (JP) 2009-11-25 EP claimed
EP-0790974-B1 SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITIORS BAYER AG (US) 2002-08-14 EP claimed
US-20260078099-A1 COMPOUND, PREPARATION METHOD THEREOF, AND LIPID NANOPARTICLE AND PHARMACEUTICAL COMPOSITION SUZHOU HEALIRNA BIOTECHNOLOGY CO., LTD. (CN) 2026-03-19 US disclosed
EP-4650349-A1 COMPOUND, PREPARATION METHOD, AND LIPID NANOPARTICLES AND PHARMACEUTICAL COMPOSITION THEREOF Suzhou Healirna Biotechnology Co., Ltd. (CN) 2025-11-19 EP disclosed
US-20250213493-A1 NANOMATERIALS COMPRISING TRIOLS BEAM THERAPEUTICS INC. 2025-07-03 US disclosed
US-12296053-B2 Nanomaterials comprising triols BEAM THERAPEUTICS INC. (US) 2025-05-13 US disclosed
EP-4540222-A1 NANOMATERIALS COMPRISING TRIOLS Beam Therapeutics Inc. (US) 2025-04-23 EP disclosed
CN-119698406-A Nanomaterials comprising triols 比姆医疗股份有限公司 2025-03-25 CN disclosed
US-4025630-A Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication ABBOTT LABORATORIES (US) 1977-05-24 US disclosed
US-4020163-A Use of heterocyclic esters of 5H-[1]benzopyrano [3,4-b]pyridines as analgesics SHARPS ASSOCIATES (US) 1977-04-26 US disclosed
US-3991194-A Heterocyclic esters of benzopyranopyridines SHARPS ASSOCIATES (US) 1976-11-09 US disclosed
US-3972880-A TRANQUILIZER SHARPS ASSOCIATES (US) 1976-08-03 US disclosed
US-3960871-A ANTIDEPRESSANT, ANALGESICS, ANTICONVULSANT ANTI-ANXIETY ACTIVITY SHARPS ASSOCIATES (US) 1976-06-01 US disclosed
US-3941782-A Heterocyclic esters of benzopyrans SHARPS ASSOCIATES (US) 1976-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PNMT, MAOA, HNMT SMN1; SMN2 2842/4885CYP1A2 116/4885MAPK1 2712/4885
US-20260078099-A1 COMPOUND, PREPARATION METHOD THEREOF, AND LIPID NANOPARTICLE AND PHARMACEUTICAL COMPOSITION SGMS1, LDLR, NR5A1 SMN1; SMN2 1014/4885CYP1A2 235/4885MAPK1 1432/4885
US-20210128498-A1 TARGETED DRUGS ASSOCIATED WITH TRIMETHYLAMINE AND/OR TRIMETHYLAMINE-N-OXIDE MAOA, PNMT, HNMT SMN1; SMN2 2279/4885CYP1A2 69/4885MAPK1 1829/4885
US-20250277012-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF SMN1; SMN2 3944/4885CYP1A2 2641/4885MAPK1 4178/4885
US-20100113450-A1 Agent for Preventing and Alleviating Wrinkles GABRB1, GABRB2, GABBR1 SMN1; SMN2 1147/4885CYP1A2 706/4885MAPK1 2400/4885
US-12296053-B2 Nanomaterials comprising triols PNPLA2, LIPA, PHOSPHO1 SMN1; SMN2 760/4885CYP1A2 3545/4885MAPK1 4328/4885
US-20250213493-A1 NANOMATERIALS COMPRISING TRIOLS PNPLA2, LIPA, PHOSPHO1 SMN1; SMN2 760/4885CYP1A2 3545/4885MAPK1 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.