Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184706 | 0.76 | HSD17B10 (0.41) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL15043614 | 0.76 | APEX1 (0.51) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL19720585 | 0.74 | CYP1A2 (0.53) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10391597 | 0.72 | APEX1 (0.49) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL31536670 | 0.72 | GLA (0.50) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7027263 | 0.72 | GLA (0.67) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL1069692 | 0.72 | — | — | |
| SCHEMBL6536452 | 0.72 | GLA (0.67) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL3973280 | 0.72 | GLA (0.67) | GLAAPEX1CYP1A2MAPK1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL9352555 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268828-B2 | Inhibitors of the chemokine receptor CxCR3 | SANOFI (FR) | 2012-09-18 | — | — | US | disclosed |
| EP-2262784-A1 | INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3 | Sanofi-Aventis (FR) | 2010-12-22 | — | — | EP | disclosed |
| US-20100305088-A1 | INHIBITORS OF THE CHEMOKINE RECEPTOR CxCR3 | SANOFI-AVENTIS (FR) | 2010-12-02 | — | — | US | disclosed |
| WO-2009105435-A1 | INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3 | SANOFI-AVENTIS (FR) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305088-A1 | INHIBITORS OF THE CHEMOKINE RECEPTOR CxCR3 | CXCR3, CXCR1, ACKR3 | GLA 4774/4885APEX1 1895/4885CYP1A2 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.