Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631604 | 0.84 | TSHR (0.71) | TSHRTHRBKDM4ENPC1RAB9A | |
| SCHEMBL19486136 | 0.79 | TSHR (0.48) | TSHRTHRBKDM4ENPC1RAB9A | |
| SCHEMBL5402930 | 0.78 | LCK (0.48) | TSHRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7847391 | 0.78 | TSHR (0.45) | TSHRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31180025 | 0.78 | TSHR (0.45) | TSHRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15214855 | 0.78 | L3MBTL1 (0.56) | KDM4ENPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL23652406 | 0.77 | KDM4E (0.55) | KDM4ENPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL9994921 | 0.77 | TSHR (0.48) | TSHRNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL7305706 | 0.74 | HTT (0.43) | TSHRKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17059040 | 0.72 | MPI (0.47) | THRBKDM4EGAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-B1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2020-06-24 | — | — | EP | disclosed |
| EP-2897959-B1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2017-12-20 | — | — | EP | disclosed |