SCHEMBL19721385

SCHEMBL19721385

CNc1ccccc1-n1[nH]c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 2/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
RECQL P46063 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PKM P14618 1/20 0.31
PSMB8 P28062 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
ATM Q13315 1/20 0.30
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21325742 0.70 HSP90AA1 (0.51) MAPTKDM4EPOLB
SCHEMBL19721379 0.66 MAPT (0.39) MAPTNPSR1KDM4EPOLBUSP2
SCHEMBL18944492 0.65 HTR1A (0.48) MAPTNPSR1POLBALDH1A1HSD17B10
SCHEMBL8350224 0.65 KDM4E (0.49) MAPTNPSR1KDM4EPOLBUSP2
SCHEMBL21912882 0.64 TSHR (0.44) MAPTKDM4EALDH1A1PKM
SCHEMBL27506463 0.63 ADRA2C (0.56) MAPTNPSR1KDM4EPOLBHSD17B10
SCHEMBL29449705 0.63 POLB (0.60) MAPTNPSR1KDM4EPOLBUSP2
SCHEMBL653948 0.63 POLB (0.60) MAPTNPSR1KDM4EPOLBUSP2
SCHEMBL21914030 0.62 HTT (0.51) POLBALDH1A1
SCHEMBL30609627 0.62 ADRB1 (0.59) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2897959-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2017-12-20 EP disclosed