SCHEMBL19722043

SCHEMBL19722043

C=C(CO)C(=O)OCCOc1ccc(C2=CCC(C3CCC(CCCCC)CC3)CC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 5/20 0.34
▸ ITGB3 P05106 6/20 0.34
▸ ITGA2B P08514 6/20 0.34
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ CASP3 P42574 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ NLRP3 Q96P20 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ HRH2 P25021 1/20 0.33
▸ HRH1 P35367 1/20 0.33
▸ ITGAV P06756 1/20 0.32
▸ CHRM2 P08172 1/20 0.32
▸ SLC6A4 P31645 1/20 0.32
▸ RARA P10276 1/20 0.32
▸ LMNA P02545 1/20 0.31
▸ NPY1R P25929 1/20 0.31
▸ NPY2R P49146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19856193 0.93 CNR1 (0.31) RARBITGB3ITGA2B
SCHEMBL19721848 0.90 RARB (0.37) RARBITGB3ITGA2BNPC1RAB9A
SCHEMBL20322951 0.88 — —
SCHEMBL19722109 0.85 TLR4 (0.31) —
SCHEMBL19722045 0.85 RAB9A (0.41) RARBITGB3ITGA2BRAB9AHRH2
SCHEMBL20882511 0.84 — —
SCHEMBL19722549 0.83 RAB9A (0.43) ITGB3ITGA2BRAB9AHRH2HRH1
SCHEMBL19722125 0.82 RAB9A (0.43) RARBITGB3ITGA2BRAB9AHRH2
SCHEMBL19856198 0.81 TLR4 (0.30) —
SCHEMBL19722609 0.80 RAB9A (0.46) ITGB3ITGA2BRAB9AHRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 — — US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 RARB 2607/4885ITGB3 2716/4885ITGA2B 3852/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 RARB 1568/4885ITGB3 3454/4885ITGA2B 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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