SCHEMBL19722067

SCHEMBL19722067

C=C(CCO)C(=O)Oc1ccc(-c2ccc(CCCCC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 5/20 0.56
▸ THRA P10827 3/20 0.53
▸ RARB P10826 9/20 0.49
▸ ALDH1A1 P00352 3/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ RARA P10276 2/20 0.48
▸ MTOR P42345 1/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ USP2 O75604 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ SLCO1B3 Q9NPD5 1/20 0.44
▸ SLCO1B1 Q9Y6L6 1/20 0.44
▸ RARG P13631 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19855164 0.91 THRB (0.46) THRBTHRARARBALDH1A1MEN1
SCHEMBL19721952 0.90 THRB (0.58) THRBTHRARARBALDH1A1MEN1
SCHEMBL19722398 0.90 THRB (0.58) THRBTHRARARBALDH1A1MEN1
SCHEMBL19722533 0.89 RARB (0.53) THRBTHRARARBALDH1A1MEN1
SCHEMBL19722229 0.88 THRB (0.57) THRBTHRARARBALDH1A1MEN1
SCHEMBL19721939 0.86 THRB (0.53) THRBTHRARARBALDH1A1MEN1
SCHEMBL19722103 0.86 RARB (0.52) THRBTHRARARBMAPTRARA
SCHEMBL19721971 0.86 THRB (0.57) THRBTHRARARBALDH1A1MEN1
SCHEMBL19721948 0.85 THRB (0.51) THRBTHRARARBALDH1A1MEN1
SCHEMBL19722497 0.85 THRB (0.56) THRBTHRARARBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 — — US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 — — US disclosed
US-20210223635-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-07-22 — — US disclosed
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-20210171831-A1 ALIGNMENT AID, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2021-06-10 — — US disclosed
US-20200224098-A1 POLYMERIZABLE MONOMER, LIQUID CRYSTAL COMPOSITION USING POLYMERIZABLE MONOMER, AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2020-07-16 — — US disclosed
US-20200208054-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (Tokyo) (JP) 2020-07-02 — — US disclosed
WO-2020008895-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT DIC株式会社 2020-01-09 — — WO disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 — — EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 — — US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 THRB 4606/4885THRA 4306/4885RARB 2607/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 THRB 4233/4885THRA 3611/4885RARB 1568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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