SCHEMBL19722444

SCHEMBL19722444

CCCCCC1CCC(C2CCC(/C=C/C3CCC(c4ccc(OC(=O)C(C)CO)cc4)CC3)CC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.38
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.34
ITGB3 P05106 4/20 0.33
ITGA2B P08514 4/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPK1 P28482 1/20 0.32
ESR2 Q92731 1/20 0.32
LSS P48449 2/20 0.32
SPHK1 Q9NYA1 2/20 0.31
TP53 P04637 1/20 0.31
ITGAV P06756 1/20 0.31
CHRM2 P08172 1/20 0.31
SLC6A4 P31645 1/20 0.31
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755096 0.83 CYP2C9 (0.38) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL10614743 0.81 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL10614736 0.81 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL21321785 0.80 DRD2 (0.44) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL19722181 0.78 NAAA (0.36) CYP2C9MAPTMEN1KMT2ATP53
SCHEMBL21298968 0.77 CYP2C9 (0.43) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL8375643 0.77 CYP2C9 (0.45) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL8375641 0.77 CYP2C9 (0.45) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL8375645 0.77 CYP2C9 (0.45) CYP2C9MAPTALDH1A1LMNARAB9A
SCHEMBL8375649 0.77 CYP2C9 (0.45) CYP2C9MAPTALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed