Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21321985 | 0.88 | TSHR (0.46) | LMNACYP3A4SMN1; SMN2MEN1USP2 | |
| SCHEMBL14926504 | 0.88 | THRA (0.53) | ALDH1A1PDE3BPDE3AP2RY12TP53 | |
| SCHEMBL14926508 | 0.86 | THRA (0.55) | ALDH1A1PDE3BPDE3AP2RY12TP53 | |
| SCHEMBL13422217 | 0.85 | PPARA (0.48) | ALDH1A1THRBPPARGPPARATHRA | |
| SCHEMBL18643843 | 0.84 | KDM4E (0.46) | LMNACYP3A4SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL19722020 | 0.83 | MEN1 (0.44) | LMNACYP3A4SMN1; SMN2MEN1USP2 | |
| SCHEMBL14926509 | 0.83 | ALDH1A1 (0.58) | ALDH1A1PDE3BPDE3AP2RY12TP53 | |
| SCHEMBL6288257 | 0.83 | MEN1 (0.55) | LMNACYP3A4SMN1; SMN2MEN1USP2 | |
| SCHEMBL14930467 | 0.82 | THRA (0.56) | ALDH1A1PDE3BPDE3AP2RY12TP53 | |
| SCHEMBL14926510 | 0.82 | THRA (0.56) | ALDH1A1PDE3BPDE3AP2RY12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257839-A1 | POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-12-20 | — | — | EP | disclosed |