Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988356 | 0.87 | CA1 (0.34) | CA12CA1CA2CA7CA14 | |
| SCHEMBL1973057 | 0.83 | CA1 (0.60) | CA12CA1CA2CA7CA14 | |
| SCHEMBL2954454 | 0.80 | CA1 (0.53) | CA12CA1CA2CA7CA14 | |
| SCHEMBL2962997 | 0.79 | ALDH1A1 (0.44) | CA12CA1CA2CA7CA14 | |
| SCHEMBL2960594 | 0.64 | ALDH1A1 (0.56) | CA12CA1CA2CA7CA14 | |
| SCHEMBL3048704 | 0.62 | CA1 (0.49) | CA12CA1CA2CA7CA14 | |
| SCHEMBL2884897 | 0.62 | L3MBTL1 (0.33) | CA12CA1CA2CA7CA14 | |
| SCHEMBL29992505 | 0.60 | FYN (0.56) | CA12CA1CA2CA7CA14 | |
| SCHEMBL22815693 | 0.60 | FYN (0.56) | CA12CA1CA2CA7CA14 | |
| SCHEMBL4565135 | 0.58 | CA1 (0.39) | CA12CA1CA2CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937675-B1 | BICYCLIC ARYL-SULFONIC ACID [1,3,4]-THIADIAZOL-2-YL-AMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS (FR) | 2011-06-22 | — | — | EP | disclosed |