SCHEMBL19724

SCHEMBL19724

COc1[c]c(OC)cc(OC)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
CYP1A1 P04798 7/20 0.42
CYP1B1 Q16678 7/20 0.42
CYP3A4 P08684 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA12 O43570 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
ABL1 P00519 3/20 0.39
ABCB1 P08183 3/20 0.39
BCR P11274 3/20 0.39
CYP1A2 P05177 4/20 0.37
CYP2E1 P05181 2/20 0.37
CYP2C8 P10632 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2A6 P11509 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP4B1 P13584 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491166 0.87 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CYP3A4CA1
SCHEMBL8629428 0.86 ESR1 (0.42) ALDH1A1CYP1A1CYP1B1CYP3A4ABL1
SCHEMBL3932720 0.83 ALDH1A1 (0.43) ALDH1A1CYP1A1CYP1B1CYP3A4CA1
SCHEMBL744029 0.83 ALDH1A1 (0.43) ALDH1A1CYP1A1CYP1B1CYP3A4CA1
SCHEMBL744349 0.83 ALDH1A1 (0.43) ALDH1A1CYP1A1CYP1B1CYP3A4CA1
SCHEMBL491242 0.83 ALDH1A1 (0.43) ALDH1A1CYP1A1CYP1B1CYP3A4CA1
SCHEMBL9444304 0.83 ALDH1A1 (0.43) ALDH1A1CYP1A1CYP1B1CYP3A4CYP1A2
SCHEMBL28421814 0.82 ALDH1A1 (0.39) ALDH1A1CYP1A1CYP1B1CYP3A4ABL1
SCHEMBL1637765 0.81 TUBB4A (0.37) ALDH1A1ESR1PTGS2TUBB4ATUBB
SCHEMBL29078261 0.79 CA1 (0.41) ALDH1A1CYP1A1CYP1B1CYP3A4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3861 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-116178267-B Chiral N-heterocyclic carbene nitrile oxide adduct organic catalyst and application thereof 大连理工大学 2024-06-28 CN claimed
CN-118125959-A Pyrrole derivative and preparation method and application thereof 南京农业大学 2024-06-04 CN claimed
EP-4349813-A1 QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Yichang Humanwell Pharmaceutical Co., Ltd. (CN) 2024-04-10 EP claimed
WO-2024060641-A1 CYCLOTRIARYLPHOSPHINE, METHOD FOR PREPARING SAME, AND USE THEREOF 东莞市均成高新材料有限公司 2024-03-28 WO claimed
CN-114797989-B Supported catalyst and preparation method and application thereof 卫星化学股份有限公司 2024-02-23 CN claimed
CN-117279892-A Quaternary amine salt compound and preparation method and application thereof 宜昌人福药业有限责任公司 2023-12-22 CN claimed
CN-117164641-A Nickel complex for synthesizing polyketone resin, preparation method and application 大连理工大学 2023-12-05 CN claimed
WO-2023221952-A1 CYCLIC QUATERNARY AMMONIUM SALT COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 宜昌人福药业有限责任公司 2023-11-23 WO claimed
US-11807620-B2 Quinazolinone compounds and related compounds Plexium, Inc. (US) 2023-11-07 US claimed
US-4342869-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-08-03 US claimed
US-4342757-A Cephalosporin antibiotic compositions MERCK & CO., INC. (US) 1982-08-03 US claimed
US-4338438-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 US claimed
US-4338437-A Cephalosporin antibiotics MERCK & CO., INC. (US) 1982-07-06 US claimed
US-4316037-A N-Benzyl and N-substituted benzyl tetrazole-5-carboxylic acids and the preparation thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1982-02-16 US claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed
US-4298741-A DETHIAPENICILLIN ANTIBIOTICS MERCK & CO., INC. (US) 1981-11-03 US claimed
US-4297488-A 7-α-Methoxy cephalosporins MERCK & CO., INC. (US) 1981-10-27 US claimed
US-4258040-A Cephalosporin compounds MERCK & CO., INC. (US) 1981-03-24 US claimed
US-4060687-A Cephalosporins having a 3-α substituted alkyl grouping MERCK & CO., INC. (US) 1977-11-29 US claimed