SCHEMBL1972402

SCHEMBL1972402

CCCc1cc(S)ccc1S

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.32
HMGCR P04035 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1970437 0.87 TYR (0.41) ALOX5
SCHEMBL1967735 0.85 TYR (0.42) ALOX5
SCHEMBL1971686 0.84 TYR (0.44) ALOX5
SCHEMBL1965348 0.84 TYR (0.44) ALOX5
SCHEMBL1969918 0.84 TYR (0.44) ALOX5
SCHEMBL1971171 0.84 TYR (0.44) ALOX5
SCHEMBL1968957 0.84 TYR (0.44) ALOX5
SCHEMBL1972040 0.81 GABRA1 (0.32)
SCHEMBL25987812 0.80 PRKCI (0.35) PRKCIHMGCR
SCHEMBL10332935 0.80 TAAR1 (0.41) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
CN-102224147-B Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2015-03-18 CN disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
CN-103382173-A Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES 2013-11-06 CN disclosed
CN-102224147-A Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2011-10-19 CN disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
EP-2334661-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS Ube Industries, Ltd. (JP) 2011-06-22 EP disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES PRKCI 3628/4885HMGCR 4692/4885ALOX5 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.