SCHEMBL1972040

SCHEMBL1972040

CCc1cc(S)ccc1S

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7041344 0.82 GRIN2D (0.36) GABRA1GABRB2ALDH1A1MAPTGRIN2D
SCHEMBL1972402 0.81 PRKCI (0.32)
SCHEMBL3012966 0.80 GABRA1 (0.32) GABRA1GABRB2GRIN2DGRIN3BGRIN1
SCHEMBL18231539 0.78 MAPT (0.39) KDM4EALDH1A1MAPT
SCHEMBL29810618 0.78 CYP2A6 (0.46) ALDH1A1MAPT
SCHEMBL11552454 0.78 KIF11 (0.36) GABRA1GABRB2KDM4EALDH1A1
SCHEMBL6652316 0.78 CYP2A6 (0.46) ALDH1A1MAPT
SCHEMBL1970437 0.78 TYR (0.41) ALDH1A1MAPT
SCHEMBL16089494 0.76 ALDH1A1 (0.43) KDM4EALDH1A1MAPT
SCHEMBL11756481 0.76 IDO1 (0.42) GABRA1GABRB2KDM4EALDH1A1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2334661-B1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS UBE INDUSTRIES (JP) 2017-08-30 EP disclosed
CN-102224147-B Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2015-03-18 CN disclosed
US-8653302-B2 Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES, LTD. (JP) 2014-02-18 US disclosed
CN-103382173-A Processes for preparing poly(pentafluorosulfanyl)aromatic compounds UBE INDUSTRIES 2013-11-06 CN disclosed
CN-102224147-A Process for preparing poly (pentafluorosulfanyl) aromatic compounds UBE INDUSTRIES 2011-10-19 CN disclosed
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds UBE INDUSTRIES, LTD. (JP) 2011-07-07 US disclosed
EP-2334661-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS Ube Industries, Ltd. (JP) 2011-06-22 EP disclosed
WO-2010033930-A1 PROCESSES FOR PREPARING POLY(PENTAFLUOROSULFANYL)AROMATIC COMPOUNDS IM&T RESEARCH, INC. (US) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166392-A1 Processes for Preparing Poly(Pentafluorosulfanyl)Aromatic Compounds PFAS, PUF60, FES GABRA1 786/4885GABRB2 1904/4885KDM4E 2437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.