Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KYAT1 | Q16773 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767611 | 0.88 | KYAT1 (0.60) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL16730420 | 0.88 | KYAT1 (0.60) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL11767616 | 0.88 | KYAT1 (0.60) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL3560757 | 0.86 | MEN1 (0.65) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL16361794 | 0.86 | MEN1 (0.65) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL3560755 | 0.86 | MEN1 (0.65) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL10410691 | 0.85 | MAPT (0.59) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL19661582 | 0.85 | KYAT1 (0.62) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL10410692 | 0.85 | MAPT (0.59) | MEN1KMT2AKYAT1NPSR1ATM | |
| SCHEMBL12442232 | 0.85 | MAPT (0.59) | MEN1KMT2AKYAT1NPSR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208036-B2 | Process for the preparation of Apixaban and intermediates thereof | UNICHEM LABORATORIES LIMITED (IN) | 2019-02-19 | — | — | US | disclosed |
| US-20170362232-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | UNICHEM LAB LTD (IN) | 2017-12-21 | — | — | US | disclosed |
| US-20170362232-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | UNICHEM LAB LTD (IN) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208036-B2 | Process for the preparation of Apixaban and intermediates thereof | HAX1, CYP4X1, HTRA1 | MEN1 1657/4885KMT2A 3158/4885KYAT1 3854/4885 |
| US-20170362232-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | HAX1, CYP4X1, HTRA1 | MEN1 1657/4885KMT2A 3158/4885KYAT1 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.