Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19726646 | 0.87 | RORC (0.53) | RORCCYP2C9CYP3A4CYP2C19 | |
| SCHEMBL17912508 | 0.84 | RORC (0.52) | RORCCYP2C9CYP3A4CYP2C19 | |
| SCHEMBL19726644 | 0.81 | RORC (0.42) | RORCCYP2C9 | |
| SCHEMBL19726641 | 0.79 | F2RL3 (0.44) | RORCCYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL19726643 | 0.79 | RORC (0.52) | RORCCYP2C9CYP3A4 | |
| SCHEMBL17912679 | 0.74 | RORC (0.54) | RORCCYP2C9CYP3A4 | |
| SCHEMBL19726647 | 0.74 | RORC (0.42) | RORCCYP2C9 | |
| SCHEMBL17912591 | 0.73 | RORC (0.61) | RORCCYP2C9CYP3A4 | |
| SCHEMBL17912699 | 0.71 | RORC (0.46) | RORCCYP2C9CYP3A4CDK4CDK2 | |
| SCHEMBL17912672 | 0.71 | RORC (0.55) | RORCCYP2C9CYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362225-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | IMPETIS BIOSCIENCES LTD. (IN) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362225-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | RORC, RORA, RORB | RORC 1/4885CYP2C9 298/4885CYP3A4 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.