Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331188 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL10417880 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL7471539 | 0.86 | L3MBTL1 (0.39) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL254822 | 0.85 | KDM4E (0.46) | SMN1; SMN2L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL21877426 | 0.83 | P2RX7 (0.51) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL4621512 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL25434306 | 0.82 | CA1 (0.61) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL151213 | 0.82 | CA1 (0.61) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL27753904 | 0.82 | CA1 (0.61) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL4958775 | 0.81 | AR (0.48) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103456982-A | Functional electrolyte for improving charge-discharge efficiency of lithium ion battery and application thereof | CHINA NAT OFFSHORE OIL CORP | 2013-12-18 | — | — | CN | claimed |
| US-5475155-A | Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation | THE DOW CHEMICAL COMPANY (US) | 1995-12-12 | — | — | US | claimed |
| WO-1995015301-A1 | PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENES AND 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENES | THE DOW CHEMICAL COMPANY (US) | 1995-06-08 | — | — | WO | claimed |
| US-20170336728-A1 | ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF | CANON KABUSHIKI KAISHA (JP) | 2017-11-23 | — | — | US | disclosed |
| CN-104981460-A | Synthesis of N-heterocyclic carbenes and intermediates thereof | UNIV ST ANDREWS | 2015-10-14 | — | — | CN | disclosed |
| EP-2390241-B1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8598349-B2 | Method for manufacturing conjugated aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-03 | — | — | US | disclosed |
| US-8293905-B2 | Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-23 | — | — | US | disclosed |
| EP-1861382-B1 | FUSED AROMATIC COMPOUNDS HAVING ANTI-DIABETIC ACTIVITY | MERCK SHARP & DOHME (US) | 2012-10-10 | — | — | EP | disclosed |
| CN-101693723-B | 3-tri-alkoxy phenyl dialkyl phosphine tetrafluoroborate and synthesis and application thereof | UNIV ZHEJIANG | 2012-09-05 | — | — | CN | disclosed |
| CN-102361845-A | Method for producing conjugated aromatic compound | SUMITOMO CHEMICAL CO | 2012-02-22 | — | — | CN | disclosed |
| US-5266577-A | Method of treating congestive heart failure using carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| US-5198448-A | Cardiovascular disorders | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| EP-0282266-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID AMIDES OR ESTERS | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5142057-A | Reacting an organic chloride with carbon monoxide and amine | NIHON NOHYAKU CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5053514-A | Side effect reduction; carbostyril derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0282266-A2 | Process for producing carboxylic acid amides or esters | NIHON NOHYAKU CO., LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0177326-A2 | 2-Arylmethyl-5-aryl-oxazolidines, their preparation and use | SMITHKLINE BEECHAM CORPORATION (US) | 1986-04-09 | — | — | EP | disclosed |
| EP-0088849-A1 | Levorotatory compounds of N-substituted benzenesulphone amides, process for their preparation and pharmaceutical compositions containing them | CHOAY S.A. (FR) | 1983-09-21 | — | — | EP | disclosed |