Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19738037 | 0.84 | POLB (0.40) | POLBALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7925816 | 0.80 | GAA (0.49) | POLBALDH1A1LMNAGAAKMT2A | |
| SCHEMBL21378598 | 0.80 | GAA (0.49) | POLBALDH1A1LMNAGAAKMT2A | |
| SCHEMBL7933300 | 0.80 | GAA (0.49) | POLBALDH1A1LMNAGAAKMT2A | |
| SCHEMBL140992 | 0.79 | STAT3 (0.46) | ALDH1A1GAAKMT2AMEN1STAT3 | |
| SCHEMBL3295031 | 0.78 | EGFR (0.40) | POLBALDH1A1GFERLMNASMN1; SMN2 | |
| SCHEMBL9484674 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL17929597 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL17480135 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL9585334 | 0.76 | CYP1A2 (0.54) | ALDH1A1LMNASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170360665-A1 | NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360665-A1 | NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF | GLA, PAH, P4HA1 | POLB 661/4885ALDH1A1 52/4885GFER 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.