Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417370 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1RXFP1POLBKDM4E | |
| SCHEMBL5823247 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1RXFP1POLBKDM4E | |
| SCHEMBL418463 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1RXFP1POLBKDM4E | |
| SCHEMBL3739039 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1RXFP1POLBKDM4E | |
| SCHEMBL5768836 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPSR1RXFP1POLBKDM4E | |
| SCHEMBL8246813 | 0.91 | GAA (0.41) | ALDH1A1NPSR1RXFP1POLBHSD17B10 | |
| SCHEMBL418068 | 0.91 | GAA (0.41) | ALDH1A1NPSR1RXFP1POLBHSD17B10 | |
| SCHEMBL9308973 | 0.91 | GAA (0.41) | ALDH1A1NPSR1RXFP1POLBHSD17B10 | |
| SCHEMBL13198671 | 0.91 | GAA (0.41) | ALDH1A1NPSR1RXFP1POLBHSD17B10 | |
| SCHEMBL418070 | 0.91 | GAA (0.41) | ALDH1A1NPSR1RXFP1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362235-A1 | ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF | VASADE BIOSCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362235-A1 | ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF | ADCY1, ADCY2, ADCY5 | ALDH1A1 531/4885NPSR1 944/4885RXFP1 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.