Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730237 | 0.95 | THRB (0.43) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19730225 | 0.93 | AKR1B1 (0.42) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19730241 | 0.92 | AKR1B10 (0.45) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19730212 | 0.92 | AKR1B10 (0.45) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19730240 | 0.92 | NPC1 (0.49) | THRBMGLLNPC1RAB9AHCAR2 | |
| SCHEMBL19730246 | 0.92 | NPC1 (0.49) | THRBMGLLNPC1RAB9AHCAR2 | |
| SCHEMBL19730223 | 0.91 | AKR1B1 (0.43) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19730216 | 0.90 | ALDH1A1 (0.46) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19730228 | 0.90 | ALDH1A1 (0.46) | THRBMGLLAKR1B1AKR1B10NPC1 | |
| SCHEMBL19738415 | 0.88 | CA12 (0.44) | THRBMGLLAKR1B1AKR1B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170364025-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE INCLUDING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-12-21 | — | — | US | disclosed |