⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060365 | 1.00 | ALDH1A1 (0.45) | — | |
| SCHEMBL10842765 | 0.97 | ALDH1A1 (0.43) | — | |
| SCHEMBL7474406 | 0.97 | — | — | |
| SCHEMBL7473454 | 0.91 | — | — | |
| SCHEMBL10353084 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL30967362 | 0.81 | — | — | |
| Maleic Acid SCHEMBL21585678 | 0.81 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL11650597 | 0.80 | ADH1B (0.31) | — | |
| SCHEMBL8985133 | 0.76 | EPHX1 (0.30) | — | |
| SCHEMBL33021 | 0.75 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006010-B1 | IMPROVED METHOD FOR PREPARING MALEATE SALT OF PARA-SUBSTITUTED CIS-CYCLOHEXYLAMINO NITRILE | HEBEI LANSHENG BIOTECH CO LTD (CN) | 2023-10-11 | — | — | EP | claimed |
| EP-4234533-A1 | CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME | Hebei Lansheng Biotech Co., Ltd (CN) | 2023-08-30 | — | — | EP | claimed |
| US-20230257341-A1 | CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINONITRILE SALT, PREPARATION METHOD THEREFOR AND USE THEREOF, AND METHOD FOR PREPARING PESTICIDE USING SAME | HEBEI LANSHENG BIOTECH CO., LTD (CN) | 2023-08-17 | — | — | US | claimed |
| CN-115427393-B | Cis-para-substituted cyclohexylamino nitrile salts, method for the production and use thereof, and method for producing pesticides using same | 河北兰升生物科技有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-115427393-A | Cis-para-substituted cyclohexylamino nitrile salts, process for their preparation and their use, and process for preparing pesticides using them | 河北兰升生物科技有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-112341362-B | Cis-para-substituted cyclohexyl amino nitrile malate, and preparation and application thereof | 永农生物科学有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114008106-A | Radiation curable compositions by anionic polymerization | 汉高股份有限及两合公司 | 2022-02-01 | — | — | CN | claimed |
| EP-3819289-A1 | CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINO NITRILE SALT AND PREPARATION METHOD THEREFOR | Hebei Lansheng Biotech Co., Ltd (CN) | 2021-05-12 | — | — | EP | claimed |
| CN-112341362-A | Cis-para-substituted cyclohexyl amino nitrile malate, and preparation and application thereof | 永农生物科学有限公司 | 2021-02-09 | — | — | CN | claimed |
| WO-2021017642-A1 | IMPROVED METHOD FOR PREPARING MALEATE SALT OF PARA-SUBSTITUTED CIS-CYCLOHEXYLAMINO NITRILE | 河北兰升生物科技有限公司 | 2021-02-04 | — | — | WO | claimed |
| CN-110691771-B | Cis-para-substituted cyclohexyl amino nitrile salt and preparation method thereof | 河北兰升生物科技有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-110294692-B | Improved preparation method of cis-para-substituted cyclohexyl amino nitrile maleate | 河北兰升生物科技有限公司 | 2020-09-01 | — | — | CN | claimed |
| CN-110691771-A | Cis-para-substituted cyclohexyl amino nitrile salt and preparation method thereof | 河北兰升生物科技有限公司 | 2020-01-14 | — | — | CN | claimed |
| WO-2019233498-A1 | CIS-PARA-SUBSTITUTED CYCLOHEXYLAMINO NITRILE SALT AND PREPARATION METHOD THEREFOR | 河北兰升生物科技有限公司 (CN) | 2019-12-12 | — | — | WO | claimed |
| EP-2334652-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-22 | — | — | EP | claimed |
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |
| EP-0124479-B1 | IMINOSULFON AMIDES AND PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS, AND THE COMPOUNDS FOR USE | CIBA-GEIGY AG (CH) | 1988-01-20 | — | — | EP | claimed |
| EP-0124479-A1 | Iminosulfon amides and processes for their preparation, pharmaceutical preparations containing such compounds, and the compounds for use | CIBA-GEIGY AG (CH) | 1984-11-07 | — | — | EP | claimed |
| CN-110354777-B | Method for preparing cis-para-substituted cyclohexylamino nitrile maleate by using reaction device of ultrasonic-assisted crystallization | 兰升生物科技集团股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |