Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 4/20 | 0.31 |
| ▸ | CCR8 | P51685 | 4/20 | 0.31 |
| ▸ | CCR5 | P51681 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763321 | 0.78 | HSP90AA1 (0.48) | LIMK1CLK1HSP90AA1L3MBTL1NPC1 | |
| SCHEMBL15595447 | 0.72 | LIMK1 (0.41) | LIMK1CLK1HSP90AA1L3MBTL1NPC1 | |
| SCHEMBL21895264 | 0.72 | GPR3 (0.43) | HSP90AA1L3MBTL1LMNAKDM4ECYP3A4 | |
| SCHEMBL3967344 | 0.72 | LIMK1 (0.41) | LIMK1CLK1HSP90AA1L3MBTL1NPC1 | |
| SCHEMBL14173744 | 0.72 | LIMK1 (0.41) | LIMK1CLK1HSP90AA1L3MBTL1NPC1 | |
| SCHEMBL10033652 | 0.69 | HSP90AA1 (0.42) | LIMK1CLK1HSP90AA1L3MBTL1NPC1 | |
| SCHEMBL19053803 | 0.69 | L3MBTL1 (0.62) | HSP90AA1L3MBTL1NPC1LMNACCR1 | |
| SCHEMBL20858439 | 0.69 | KDM4E (0.36) | LIMK1CLK1LMNAKDM4EMAPT | |
| SCHEMBL19731973 | 0.69 | LIMK1 (0.34) | LIMK1CLK1LMNAKDM4EMAPT | |
| SCHEMBL10054253 | 0.69 | LIMK1 (0.57) | LIMK1CLK1HSP90AA1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968229-B2 | Seven-membered ring compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| US-20170362241-A1 | 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | IDEMITSU KOSAN CO., LTD. (JP) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | MCM7, XPO7, LUC7L2 | LIMK1 2390/4885CLK1 4500/4885HSP90AA1 4264/4885 |
| US-10968229-B2 | Seven-membered ring compounds | MCM7, XPO7, LUC7L2 | LIMK1 2390/4885CLK1 4500/4885HSP90AA1 4264/4885 |
| US-20170362241-A1 | 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) | OCIAD1, OCIAD2, DDT | LIMK1 1025/4885CLK1 3452/4885HSP90AA1 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.