Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973731 | 0.94 | ZDHHC20 (0.40) | HCAR2ZDHHC20PPARG | |
| SCHEMBL147781 | 0.88 | CES1 (0.40) | APEX1CES1CES2PPARG | |
| SCHEMBL147780 | 0.88 | CES1 (0.40) | APEX1CES1CES2PPARG | |
| SCHEMBL905414 | 0.88 | CES1 (0.40) | APEX1CES1CES2PPARG | |
| SCHEMBL2153424 | 0.83 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL5885411 | 0.83 | APEX1 (0.37) | APEX1CES1CES2PPARG | |
| SCHEMBL1275312 | 0.83 | AKR1B1 (0.45) | APEX1CES1CES2PPARG | |
| SCHEMBL1275314 | 0.83 | AKR1B1 (0.45) | APEX1CES1CES2PPARG | |
| SCHEMBL1602950 | 0.82 | GPR84 (0.47) | APEX1CES1CES2PPARG | |
| SCHEMBL487304 | 0.82 | GPR84 (0.47) | APEX1CES1CES2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803473-B1 | Adhesive including medicament | UNIV LOMA LINDA MED (US) | 2011-06-22 | — | — | EP | claimed |
| EP-1409033-B1 | ADHESIVE INCLUDING MEDICAMENT | UNIV LOMA LINDA MED (US) | 2006-12-27 | — | — | EP | claimed |
| EP-1100553-B1 | MOISTURE-CURABLE ADHESIVE SUTURE STRIP | ADVANCED THERAPEUTIC TECHNOLOG (CA) | 2002-06-26 | — | — | EP | claimed |