Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21013748 | 0.77 | L3MBTL1 (0.35) | TDP1L3MBTL1ATRLCK | |
| SCHEMBL19333209 | 0.77 | L3MBTL1 (0.35) | TDP1L3MBTL1ATRLCK | |
| SCHEMBL28079387 | 0.74 | L3MBTL1 (0.58) | TDP1L3MBTL1ADORA1ADORA3ADORA2A | |
| SCHEMBL30478423 | 0.73 | CKS1B (0.53) | TDP1L3MBTL1ADORA1ADORA2AMAPT | |
| SCHEMBL2036410 | 0.73 | CKS1B (0.53) | TDP1L3MBTL1ADORA1ADORA2AMAPT | |
| SCHEMBL21013746 | 0.72 | L3MBTL1 (0.33) | TDP1L3MBTL1CNR2ATRLCK | |
| SCHEMBL19333210 | 0.72 | L3MBTL1 (0.33) | TDP1L3MBTL1CNR2ATRLCK | |
| SCHEMBL31364011 | 0.70 | TDP1 (0.53) | TDP1L3MBTL1ADORA1ADORA3ADORA2A | |
| SCHEMBL7567737 | 0.68 | CKS1B (0.43) | L3MBTL1ADORA1ADORA2AMAPT | |
| SCHEMBL28283878 | 0.67 | ADORA2A (0.48) | TDP1L3MBTL1ADORA1ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362245-A1 | TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362245-A1 | TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES AS LSD1 INHIBITORS | KDM1B, KDM5A, KDM1A | TDP1 195/4885L3MBTL1 418/4885ADORA1 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.