Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660049 | 1.00 | USP2 (0.52) | USP2GAAGRK2ROCK1HTT | |
| SCHEMBL2570938 | 1.00 | USP2 (0.52) | USP2GAAGRK2ROCK1HTT | |
| SCHEMBL19752623 | 0.85 | GUSB (0.64) | GAAL3MBTL1PKMALDH1A1KDM4E | |
| SCHEMBL19752687 | 0.85 | GUSB (0.64) | GAAL3MBTL1PKMALDH1A1KDM4E | |
| SCHEMBL19732957 | 0.84 | GAA (0.67) | USP2GAAGRK2ROCK1HTT | |
| SCHEMBL19732950 | 0.84 | GAA (0.67) | USP2GAAGRK2ROCK1HTT | |
| SCHEMBL19732951 | 0.84 | GAA (0.67) | USP2GAAGRK2ROCK1HTT | |
| SCHEMBL19752697 | 0.83 | ALDH1A1 (0.68) | GAAL3MBTL1ALDH1A1MAPTCA12 | |
| SCHEMBL19752699 | 0.83 | ALDH1A1 (0.68) | GAAL3MBTL1ALDH1A1MAPTCA12 | |
| SCHEMBL14413255 | 0.82 | PKM (0.68) | USP2GAAHTTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |