Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732940 | 1.00 | GUSB (0.77) | GUSBUSP2TSHRHTTMAPT | |
| SCHEMBL19752625 | 0.85 | GUSB (0.80) | GUSBTSHRPKMKIF11PTGES | |
| SCHEMBL19752624 | 0.85 | GUSB (0.80) | GUSBTSHRPKMKIF11PTGES | |
| SCHEMBL2572783 | 0.84 | TSHR (0.66) | GUSBUSP2TSHRMAPTALDH1A1 | |
| SCHEMBL14413255 | 0.83 | PKM (0.68) | GUSBUSP2HTTPKMKIF11 | |
| SCHEMBL19732936 | 0.83 | PKM (0.68) | GUSBUSP2HTTPKMKIF11 | |
| SCHEMBL3398149 | 0.82 | KIF11 (0.71) | GUSBUSP2HTTSMN1; SMN2PKM | |
| SCHEMBL19732923 | 0.81 | USP2 (0.79) | USP2TSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL19732955 | 0.81 | USP2 (0.79) | USP2TSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL13789190 | 0.81 | USP2 (0.79) | USP2TSHRMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260446-A1 | ENANTIOSELECTIVE SYNTHESIS OF DIHYDROPYRIMIDINONES AND HEXAHYDROPYRIMIDINONES | Universitat de les Illes Balears (ES) | 2017-12-27 | — | — | EP | disclosed |