Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173918 | 0.89 | DHFR (0.74) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL19732955 | 0.85 | USP2 (0.79) | HSD17B10ALDH1A1USP2TDP1 | |
| SCHEMBL19732923 | 0.85 | USP2 (0.79) | HSD17B10ALDH1A1USP2TDP1 | |
| SCHEMBL13789190 | 0.85 | USP2 (0.79) | HSD17B10ALDH1A1USP2TDP1 | |
| SCHEMBL20522105 | 0.85 | DHFR (0.81) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL8328481 | 0.85 | USP2 (0.58) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL6348122 | 0.85 | HTT (0.75) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL14413255 | 0.85 | PKM (0.68) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL19732936 | 0.85 | PKM (0.68) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 | |
| SCHEMBL5341216 | 0.83 | KIF11 (1.00) | KIF11HSD17B10ALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |