SCHEMBL19733036

SCHEMBL19733036

CNc1cccc[n+]1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.36
ALDH1A1 P00352 4/20 0.36
RECQL P46063 1/20 0.36
TSHR P16473 4/20 0.34
NAPRT Q6XQN6 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LMNA P02545 3/20 0.33
KDM4E B2RXH2 2/20 0.32
ATM Q13315 2/20 0.32
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP3A4 P08684 2/20 0.31
ALOX5 P09917 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19733000 0.82 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1RECQLTSHRNAPRT
Bromide SCHEMBL11753861 0.71 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1RECQLLMNAKDM4E
SCHEMBL4605088 0.70 ALDH1A1 (0.35) SMN1; SMN2ALDH1A1RECQLTSHRNAPRT
SCHEMBL28050226 0.68 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1TSHRNAPRTLMNA
SCHEMBL11287268 0.68 TSHR (0.36) ALDH1A1RECQLTSHRNAPRTHSD17B10
SCHEMBL12170287 0.67
Hydrochloric Acid SCHEMBL5315059 0.67 TP53 (0.38) SMN1; SMN2ALDH1A1TSHRPOLBHSP90AA1
SCHEMBL25470756 0.66
SCHEMBL5076504 0.66
Perchlorate SCHEMBL1121942 0.63 CA1 (0.37) TP53CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017216498-A1 CO2 RECOVERY VEOLIA RECHERCHE ET INNOVATION (FR) 2017-12-21 WO disclosed