Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294843 | 0.82 | MAPT (0.36) | TSHRMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL22492931 | 0.80 | CA2 (0.33) | TSHRMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL4605088 | 0.74 | ALDH1A1 (0.35) | TSHRMAPTPOLBCYP3A4PARP1 | |
| Bromide SCHEMBL11753861 | 0.71 | SMN1; SMN2 (0.39) | POLBRECQLRAB9ALMNAALDH1A1 | |
| SCHEMBL19733036 | 0.68 | SMN1; SMN2 (0.36) | TSHRMAPTPOLBCYP3A4RECQL | |
| Hydrochloric Acid SCHEMBL5315059 | 0.67 | TP53 (0.38) | TSHRMAPTPOLBL3MBTL1RAB9A | |
| SCHEMBL7052821 | 0.66 | ALDH1A1 (0.34) | TSHRMAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL18541275 | 0.66 | KDM4E (0.46) | TSHRMAPTPOLBCYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL27988918 | 0.66 | LMNA (0.41) | L3MBTL1LMNAALDH1A1CES2CES1 | |
| SCHEMBL26870481 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059683-A2 | 7-Acylamido-3-cephem-4-carboxylic acids, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-08 | — | — | EP | disclosed |