SCHEMBL28050226

SCHEMBL28050226

O=C(O)c1cccc[n+]1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
NAPRT Q6XQN6 2/20 0.39
DAO P14920 1/20 0.39
TSHR P16473 1/20 0.39
ALOX15 P16050 1/20 0.39
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPK1 P28482 1/20 0.33
SRD5A2 P31213 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
HMGB1 P09429 1/20 0.33
HPGD P15428 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052821 0.90 ALDH1A1 (0.34) ALDH1A1NAPRTDAOTSHRALOX15
SCHEMBL11291960 0.83 MAPT (0.38) ALDH1A1NAPRTDAOTSHRALOX15
SCHEMBL11287265 0.77 ALDH1A1 (0.39) ALDH1A1NAPRTDAOTSHRALOX15
Bromide SCHEMBL11753861 0.76 SMN1; SMN2 (0.39) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL14628782 0.74 ALDH1A1 (0.40) ALDH1A1NAPRTDAOTSHRALOX15
SCHEMBL4605088 0.74 ALDH1A1 (0.35) ALDH1A1NAPRTDAOTSHRALOX15
SCHEMBL1489277 0.73 KDM4E (0.44) ALDH1A1NAPRTDAOTSHRALOX15
SCHEMBL11287268 0.73 TSHR (0.36) ALDH1A1NAPRTDAOTSHRALOX15
SCHEMBL13113036 0.73 HDAC8 (0.43) ALDH1A1NAPRTDAOTSHRALOX15
Hydrochloric Acid SCHEMBL11768005 0.71 HDAC8 (0.41) ALDH1A1NAPRTDAOTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105254872-B A kind of Semi-aromatic transparent polyamide and its synthetic method containing pyridine heterocycle 郑州大学 2018-03-06 CN claimed
CN-105254872-A Pyridine-containing heterocyclic semi-aromatic transparent polyamide and synthesis method thereof UNIV ZHENGZHOU 2016-01-20 CN claimed
CN-105254872-B A kind of Semi-aromatic transparent polyamide and its synthetic method containing pyridine heterocycle 郑州大学 2018-03-06 CN disclosed
CN-105254872-A Pyridine-containing heterocyclic semi-aromatic transparent polyamide and synthesis method thereof UNIV ZHENGZHOU 2016-01-20 CN disclosed