Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15318883 | 0.87 | KMT2A (0.36) | FKBP1ATOP2A | |
| SCHEMBL15318882 | 0.87 | KMT2A (0.36) | FKBP1ATOP2A | |
| SCHEMBL19733021 | 0.84 | FKBP1A (0.32) | FKBP1ATOP2ADUT | |
| SCHEMBL28714852 | 0.84 | FKBP1A (0.32) | FKBP1ATOP2ADUT | |
| SCHEMBL19733052 | 0.81 | FKBP1A (0.33) | FKBP1ATOP2ADUT | |
| SCHEMBL28936445 | 0.81 | FKBP1A (0.33) | FKBP1ATOP2ADUT | |
| SCHEMBL19733035 | 0.74 | DUT (0.36) | FKBP1ATOP2ADUT | |
| SCHEMBL28699542 | 0.74 | DUT (0.36) | FKBP1ATOP2ADUT | |
| SCHEMBL21873983 | 0.72 | FKBP1A (0.36) | FKBP1ATOP2ADUT | |
| SCHEMBL19990027 | 0.72 | PSEN1 (0.43) | FKBP1ATOP2ADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834239-B1 | HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS | ENTASIS THERAPEUTICS LTD (GB) | 2017-12-27 | — | — | EP | disclosed |